{"id":1099,"date":"2022-05-24T16:19:00","date_gmt":"2022-05-24T14:19:00","guid":{"rendered":"https:\/\/makit.edu.umontpellier.fr\/?p=1099"},"modified":"2024-02-28T10:27:38","modified_gmt":"2024-02-28T09:27:38","slug":"kateryna-makovas-event-montpellier-non-b-dna-day-9-june-2022","status":"publish","type":"post","link":"https:\/\/makit.edu.umontpellier.fr\/fr\/2022\/05\/24\/kateryna-makovas-event-montpellier-non-b-dna-day-9-june-2022\/","title":{"rendered":"Montpellier non-b dna day"},"content":{"rendered":"

Thursday 9 June (8:30 \u2013 17:00)<\/strong><\/p>\n\n\n\n

This event will focus on Non-B (non-canonical) DNA,\u2018the blessing and the curse\u2019 of the genome<\/strong>. The research over the last decade clearly demonstrated that non-B DNA forms in living cells, is ubiquitous across the tree of life, and is important for multiple molecular processes. Non-B DNA forms transiently (at 13% of the human genome, for example!) and is involved in regulation of<\/p>\n\n\n\n

replication, transcription, and translation. The program of the symposium consists of invited talks about the central and essential role of non-B DNA in organisms from viruses and plasmodium to plants and animals, including humans. Applications to human diseases, agriculture, and evolution will be covered.<\/p>\n\n\n\n

WHO SHOULD ATTEND?<\/em><\/p>\n\n\n\n

\u2013 If you have not heard about non-B DNA, we will have a tutorial for you<\/em><\/p>\n\n\n\n

\u2013 If you would like to learn how non-B is related to your research (it most likely is)<\/em><\/p>\n\n\n\n

\u2013 If you work on non-B DNA and would like to meet the non-B DNA community in Montpellier and<\/em><\/p>\n\n\n\n

establish new collaborations<\/em><\/p>\n\n\n\n

\u2013 If you want to learn something new and get a free lunch <\/em><\/p>\n\n\n\n

Programme and speakers<\/em><\/strong><\/p>\n\n\n\n

08:30 \u2013 09:00 Welcome coffee<\/em><\/p>\n\n\n\n

09:00 \u2013 09:30 Tutorial: \u2018What is non-B DNA?\u2019<\/strong><\/p>\n\n\n\n

09:30 \u2013 10:10 Keynote address:<\/strong>\u2018<\/em>The regulatory role of G-quadruplexes at promoters: Focus on HIV<\/em>\u2019<\/em>\u2013<\/strong>Sara Richter<\/strong><\/a>, University of Padova, Italy<\/p>\n\n\n\n

10:10 \u2013 10:30<\/strong>\u2018The role of G4s in mammalian replication origins\u2019<\/em>\u2013Marcel Mechali<\/strong><\/a>, Institute of Human Genetics (IGH), France<\/p>\n\n\n\n

10:30 \u2013 11:00 Coffee break<\/em><\/p>\n\n\n\n

11:00 \u2013 11:20<\/strong>\u2018G4, R-loops, and mutagenesis in plasma cell cancers\u2019<\/em>\u2013Laure Dutrieux<\/strong><\/a>, Institute of Human Genetics (IGH), France<\/p>\n\n\n\n

11:20 \u2013 11:40<\/strong>\u2018Non-B DNA and evolution\u2019<\/em>\u2013Kateryna Makova<\/strong><\/a>, Penn State University, USA & MAK\u2019IT Fellow (JRU \u2018ISEM\u2019)<\/p>\n\n\n\n

11:40 \u2013 12:00<\/strong>\u2018G-quadruplexes as promoter elements that function by excluding nucleosomes\u2019<\/em>\u2013Jean-Christophe Andrau<\/strong><\/a>, Institute of Molecular Genetics of Montpellier (IGMM), France<\/p>\n\n\n\n

12:00 \u2013 12:20<\/strong>\u2018Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network\u2019<\/em>\u2013Charles Lecellier<\/strong><\/a>, Institute of Molecular Genetics of Montpellier (IGMM) & Laboratory of Computer Science, Robotics and Microelectronics of Montpellier (LIRMM), France<\/p>\n\n\n\n

12:20 \u2013 13:20 Lunch break<\/em><\/p>\n\n\n\n

13:20 \u2013 13:40<\/strong> \u2018G4 sequences and DNA biology in malaria parasites\u2019<\/em>\u2013Jose-Juan Lopez-Rubio<\/strong><\/a>, Laboratory of Pathogen Host Interactions (LPHI), France<\/p>\n\n\n\n

13:40 \u2013 14:00<\/strong> \u2018Machine learning for the identification of low complexity regions involved in Transcription Factor binding\u2019<\/em>\u2013Laurent Brehelin<\/strong><\/a>, Laboratory of Computer Science, Robotics and Microelectronics of Montpellier (LIRMM), France<\/p>\n\n\n\n

14:00 \u2013 14:20<\/strong> \u2018G4-access and the role of G4s in imprinting\u2019<\/em>\u2013Cyril Esnault<\/strong><\/a>, Institute of Molecular Genetics of Montpellier (IGMM), France<\/p>\n\n\n\n

14:20-14:50<\/strong> Roundtable discussion: \u2018The role of non-B DNA in evolution\u2019<\/strong><\/p>\n\n\n\n

Moderator:Fr\u00e9d\u00e9ric Brunet<\/strong><\/a>, \u00c9cole Normale Sup\u00e9rieure de Lyon, France<\/p>\n\n\n\n

Panelists:Nicolas Galtier<\/strong><\/a>, Institute of Evolutionary Sciences of Montpellier (ISEM), France<\/p>\n\n\n\n

Nicolas N\u00e8gre<\/strong><\/a>, Diversity, Genomes and Insects-Microorganisms Interactions (DGIMI), France<\/p>\n\n\n\n

Mark Stoneking<\/strong><\/a>, Biometry and Evolutionary Biology Laboratory (LBBE), Lyon, France<\/p>\n\n\n\n

14:50 \u2013 15:20<\/em> Coffee break<\/em><\/p>\n\n\n\n

15:20 \u2013 15:40<\/strong>\u2018Regulation of RNA G4s impacting mitochondrial function\u2019 \u2013<\/em>St\u00e9fania Millevoi<\/strong><\/a>, Cancer Research Centerof Toulouse (CRCT), France<\/p>\n\n\n\n

15:40 \u2013 16:00<\/strong> \u2018The functional role of RNA G-quadruplex in plant growth\u2019<\/em>\u2013Yiliang Ding<\/strong><\/a>, John Innes Centre, UK<\/p>\n\n\n\n

16:00 \u2013 16:20<\/strong> \u2018The relevance of G4s for DNA repair after UV irradiation\u2019<\/em>\u2013Katrin Paeschke<\/strong><\/a>, University Hospital Bonn, Germany<\/p>\n\n\n\n

16:20 \u2013 16:40<\/strong> \u2018Quadruplexes are everywhere\u2019<\/em>\u2013Jean-Louis Mergny<\/strong><\/a>, Polytechnic Institute of Paris, France<\/p>\n\n\n\n

16:40 \u2013 17:00<\/strong>Closing remarks<\/p>","protected":false},"excerpt":{"rendered":"

Thursday 9 June (8:30 \u2013 17:00) This event will focus on Non-B (non-canonical) DNA,\u2018the blessing and the curse\u2019 of the genome. The research over the last decade clearly demonstrated that non-B DNA forms in living cells, is ubiquitous across the tree of life, and is important for multiple molecular processes. Non-B DNA forms transiently (at…<\/p>","protected":false},"author":1087,"featured_media":1013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[29229,29407],"tags":[],"class_list":["post-1099","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-en","category-seminar"],"acf":[],"_links":{"self":[{"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/posts\/1099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/users\/1087"}],"replies":[{"embeddable":true,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/comments?post=1099"}],"version-history":[{"count":0,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/posts\/1099\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/media\/1013"}],"wp:attachment":[{"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/media?parent=1099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/categories?post=1099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/makit.edu.umontpellier.fr\/fr\/wp-json\/wp\/v2\/tags?post=1099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}