Microbial evolutionary genomics and data analysis
Tuesday 17 May: Mini-symposium on microbial evolutionary genomics
Due to proliferation of new data generation technologies, microbial biology has become a data driven science. Yet there is still a limited “mixing” between researchers studying biological questions and their computational colleagues. The goal of this mini-symposium is to bring together representatives of the two sides (“wet” and “dry”) and discover the ways in which they can be more aware of each other’s challenges and priorities. The unique combination of speakers will cover the following areas:
- Analysis of microbial communities
- Experimental evolution
- Phylogenetic reconstruction
- Analysis of recombination
- Analysis of selection
- Data logistics and analysis automation
Programme and speakers
09:00 – 09:10Welcome and introduction
09:10 – 09:45‘Dynamics and evolution of microbialcommunities’–Ellie Harrison, University of Sheffield, UK
09:45 – 10:05 ‘Analysis of microbial communities’–Lois MaignienUniversity of Western Brittany, France
10:05 – 11:00‘Global analytical environment for me’–Saskia Hiltemann, Erasmus MC, The Netherlands
10:25 – 10:30 Coffee break
11:00– 11:20‘Evolutionary dynamics of antiobiotic resistance’–Stéphanie Bedhomme, CNRS/ Centre for Functional and Evolutionary Ecology (CEFE), France
11:20 – 11:40‘Codon bias and antibiotic resistance’–Martijn Callens, Ghent University, Belgium
11:40 – 12:00‘Experimental evolution’–Mike Finnegan, CNRS/Centre for Functional and Evolutionary Ecology (CEFE), France
12:00 – 12:20‘Coevolutionary dynamics between phages and CRISPR immunity’–Sylvain Gandon, CNRS/ Centre for Functional and Evolutionary Ecology (CEFE), France
12:20– 14:00 Lunch break
14:00 – 14:20‘Molecular evolution and selection analysis’–Sergei Kosakovsky Pond, Temple University, USA
14:20 – 14:40‘Synthetic biology’–Guillaume Cambray, CNRS/Centre for Structural Biology (CBS), France
14:40 – 15:00‘Large scale analysis of pandemic data’–Wolfgang Maier, University of Freiburg, Germany
15:00 – 15:20‘Data analytics and representation’–Maximilan Haeussler, UC Santa Cruz, USA
15:20 – 15:40‘Data analysis frameworks for microbial genomics’–Anton Nekrutenko, Pennsylvania State University, USA & MAK’IT Fellow (JRU CEFE)
15:40 – 15:50Closing remarks
15:50 -16:30 Coffee break
Wednesday 18 May: Workshop on microbial data analysis
The workshop will focus on the application of sequencing data (Illumina, Oxford Nanopore, PacBio) to analysis of microbial communities, genome assembly, analysis of variation, and identification of sites under selection.
9:00 – 12:00 – Part 1
12:00 – 13:30 – Lunch break
13:30 – 16:00 – Part 2
Presenters:
- Saskia Hiltemann – Erasmus MC, The Netherlands
- Helena Rasche – Erasmus MC & Avans Hogeschool, The Netherlands
- Anton Nekrutenko – Pennsylvania State University, USA & MAK’IT Fellow (JRU CEFE)
- Wolfgang Maier – University of Freiburg, Germany