Brain and heart diseases: connections, risks and impacts on society

An emerging field of research focuses on the interaction between the brain and the heart. While both brain and heart diseases are independently leading causes of death in the world, the relationship between the two remains largely unknown. There is, however, mounting clinical and experimental evidence that suggests a relationship between some forms of brain damage and heart dysfunction, especially considering the numerous nerves, blood vessels, and signaling molecules that connect these two important organs. Thus, it could be clinically important to determine if and to what extent heart failure can be triggered by brain injury and vice versa.

The purpose of this symposium is to bring together researchers interested in heart and brain health in order to improve understanding of similar underlying mechanisms, develop collaborations, and increase public awareness.

Programme and speakers

09:30 – 10:30 Welcome coffee and introductions

Opening of the event –Craig Goergen,Fulbright US Scholar, Purdue University, USA & MAK’IT Fellow (JRU ‘PhyMedExp’), France

Presentation of the Montpellier Advanced Knowledge Institute on Transition (MAK’IT) –Marianne Chaumel, MAK’IT Project Manager, France

Presentation of IPAM/JRU ‘PhyMedExp’/Biocampus –Pierre Sicard, INSERM/ JRU ‘PhyMedExp’, France

10:30 – 12:00 Session 1: Physiology and Function

Sylvain Richard, CNRS/JRU ‘PhyMedExp’, France – ‘Cardiac Disease: From Genetics to Consequences of Injury’

Nicola Marchi, CNRS/JRU ‘IGF’, France – ‘Neurovascular Dysfunction in Rugby Players with History of Traumatic Brain Injury’

Thomas Moore-Morris,INSERM / JRU ‘IGF’, France – ‘Targeting Fibrosis in Heart Failure’

12:00 – 13:30 Lunch

13:30 – 15:00 Session 2:Imaging and Mechanics

Miquel Aguirre, Saint-Etienne School of Mines, France – ‘Real-Time Endovascular Device Deployment Modelling Using Machine Learning Based Reduced Order Techniques’

Colleen Crouch, University of Tennessee, USA – ‘Mass Spectrometry Imaging in Cardiovascular and Neurological Studies: Combining Biomechanics with Molecular Imaging’

Deva Chan, Purdue University, USA – ‘MRI Tagging for Brain Biomechanics’

15:00 – 15:30 Coffee break

15:30 – 17:00Session 3: Development and Disease

Erin Mulvihill,University of Ottawa Heart Institute, Canada – ‘Inter-Organ Communication in Cardiovascular Disease: Discerning a Role for Hepatic DPP4’

Stephanie Lindsey, University of California San Diego, USA – ‘Assessing Cardiac Function and Treatment Strategies from Development to the Pediatric Population’

Craig Goergen, Fulbright US Scholar, Purdue University, USA & MAK’IT Fellow (JRU ‘PhyMedExp’), France –‘Cardiovascular 4D Ultrasound and Photoacoustic Murine Imaging’

17:00– 17:30Discussion and wrap-up

With the participation of Sarah Burris, FUJIFILM VisualSonics